Understanding what needs to change
We combine evidence, economics and analysis to uncover how global health ecosystems work, where the gaps lie and where the opportunities are.

How we see what's really happening
We select and combine methods from a range of research and analytical approaches so we can tell you what's changing, what's getting in the way and where action or investment can make the greatest difference.
Landscape
& diagnosis
We map systems, markets, stakeholders, funding flows and R&D pipelines to identify gaps, bottlenecks and opportunities.
Evidence
synthesis
We bring together research, data and stakeholder insight to establish what is known, what is changing and where evidence is missing.
Impact
assessment
We combine quantitative and qualitative evidence to understand what has changed, why it changed and the contribution of particular investments or programmes.
Modelling
& analysis
We model health, economic and societal impact, test different scenarios and quantify the potential returns from different choices.
Investing in health R&D
Africa's next economic growth frontier
In partnership with Africa CDC, Enabel and the EU's Global Gateway, we developed a landmark African continental investment case. Investing in health R&D drives economic growth, creates millions of skilled jobs, attracts private investment and reduces import dependency.


Strengthening the R&D ecosystem
Generating the evidence to advance new snakebite treatments
In partnership with DNDi, The END Fund, VenomAid Diagnostics, and Uniting to Combat Neglected Tropical Diseases, we are modelling the prospective health and economic impact of a new innovation landscape for treating snakebites. This will help to accelerate the development of better tools and treatments and ensure they reach the communities that need them most.
What this work delivers
A clear view of the landscape
See the key players, funding, evidence, capabilities and connections - and where the most important gaps and opportunities lie.
A better basis for decisions
Understand what is driving progress, what is getting stuck in bottlenecks and where action or investment can make the greatest difference.
Evidence you can use
Clear findings and practical recommendations that can inform strategy, policy, investment and advocacy.
Our approach
Research designed to be used
We don't produce research to sit on a shelf.
We design it around the decisions people need to make. We bring together the right evidence, expertise and perspectives to make complex choices clearer.
We want to help people change the system for the better.
Partner with us to
build better
Drop us a line if you'd like to find out more about our work, join us on projects, have a challenge or an idea

